تظاهرات سندرم آلگرو (allgrove syndrome) بدنبال اسهال و استفراغ

Authors

نادره طایی

nadereh taee department of pediatrics,faculty of medicine, lorestan university of medical sciences, khorramabad ,iranخرم آباد، بیمارستان شهید مدنیسازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (lorestan university of medical sciences) فرزانه عباسی

farzaneh abbassi department of endocrine and pediatric metabolics, tehran university of medical sciences,tehran, iranگروه غدد و متابولیک اطفال، بیمارستان شریعتی، دانشگاه علوم پزشکی تهرانسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) فریبا طرهانی

fariba tarhani department of pediatrics,faculty of medicine, lorestan university of medical sciences, khorramabad ,iranگروه اطفال، دانشکده پزشکی، دانشگاه علوم پزشکی لرستانسازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (lorestan university of medical sciences)

abstract

سندرم آلگرو (allgrove syndrome) ،سندرم تریپل آ یا نقص فامیلی گلوکوکورتیکوئید یک نقص ژنتیکی نادر با توارث اتوزوم مغلوب است و اولین بار درسال1978 توسط الگرو و همکارانش گزارش گردید. سندرم آلگرو با فقدان اشک (آلاکریما )، نقص ایزوله گلوکوکورتیکوئید و آشالازی قسمت تحتانی مری شناسایی می شود. یافته های عصبی و پوستی نیز درتعدادی از بیماران دیده می شود. افزایش رنگدانه پوستی و فقدان اشک از یافته های کلیدی در تشخیص سندرم آلگرو است. در این مقاله دختر 2 ساله ای که بدنبال ابتلا به اسهال و استفراغ دچار افزایش رنگدانه پوست شد،گزارش می شود.

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جلد ۱۳، شماره ۲، صفحات ۱۰۵-۱۱۱

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